Dave5

[Andrew] Huberman explains that psilocybin binds strongly to our serotonin 2A receptors due to their similar chemical structures, and this bond leads to alterations in perception, mood, and cognition.

A large amount of our brains’ 5HT2A receptors are located in the neo-cortex, which includes the prefrontal cortex and areas that mediate sensation.

One specific area has the largest concentration of 5HT2A receptors: the visual cortex. Under the effects of psilocybin, our visual cortex becomes more sensitive to visual stimuli, which is why patterns and shapes look more defined, movement looks more fluid, and colors become more vivid.

This also partially explains why psilocybin produces hallucinations, as it can disrupt how our brain processes visual information, especially in higher doses.

https://psychedelicspotlight.com/why-do-we-feel-like-we-can-score-40-20-in-visual-acuity-on-low-doses-of-psychedelics/